Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

VPREB1

External links	Primary Information
MGI:98936 ENSMUSG00000059305	Gene Symbol	Vpreb1
	Affected Anatomical Systems	hematopoietic system phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:1859923 Vpreb1tm1Ilm Targeted (knock-out) targeted mutation 1, Inga-Lill Martensson 10221657 MGI:2677163 Vpreb1tm1Shim Targeted (knock-out) targeted mutation 1, Takeyuki Shimizu 12055243
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Arrested B Cell Differentiation Vpreb1tm1Ilm>/Vpreb1 involves: 129P2/OlaHsd * C57BL/6 10221657 Abnormal Pre-B Cell Morphology Vpreb1tm1Ilm>/Vpreb1 involves: 129P2/OlaHsd * C57BL/6 10221657 Increased Pre-B Cell Number Vpreb1tm1Ilm>/Vpreb1 B6.129P2-Vpreb1 16361315 Decreased Pre-B Cell Number Vpreb1tm1Ilm>/Vpreb1 B6.129P2-Vpreb1 16361315