AICDA
Primary Info
Mutation
Mouse studies
DNA sequencing


mRNA IDs Primary Information
NM_020661.1 Gene Symbol AICDA
Protein Name Activation-induced cytidine deaminase
Alternate Names AID, ARP2, CDA2, HIGM2
Gene Locus 12p13

External links
IDR HPRD OMIM Entrez Gene NetPath Reactome PDB HGNC Ensembl Swiss-Prot RefDIC
17 05585 605257 57379 -
13203 ENSG00000111732 Q9GZX7 AICDA

Disease name Characteristic / Associated features Category inheritance type
Activation-induced cytidine deaminase deficiency Recurrent upper and lower respiratory tract infections; Gastrointestinal infections;Low-absent IgG, IgA; Normal-elevated IgM; Impaired Ig class switch recombination (CSR); Lymphadenopathy; Giant germinal centers in lymph nodes; Normal number of B cells; Defective generation of somatic hypermutations (SHM); Recurrent bacterial infections; No opportunistic infections Predominantly antibody deficiencies Autosomal recessive