Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

ADA

External links	Primary Information
MGI:87916 ENSMUSG00000017697	Gene Symbol	Ada
	Affected Anatomical Systems	cellular phenotype,growth/size phenotype,hematopoietic system phenotype,homeostasis/metabolism phenotype,immune system phenotype,lethality-postnatal,lethality-prenatal/perinatal,liver/biliary system phenotype,normal phenotype,renal/urinary system phenotype,respiratory system phenotype,skeleton phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:1857117 Adatm1Mw Targeted (knock-out) targeted mutation 1, Maki Wakamiya 7731963 MGI:2155977 Adatm1Vlr Targeted (knock-out) targeted mutation 1, Dinko Valerio 7670465
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Abnormal Penile Erection Function Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 18340377 Priapism Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 18340377 Abnormal Liver Morphology Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Abnormal Hepatocyte Morphology Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Small Liver Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Decreased Body Weight Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Decreased Hepatocyte Number Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Hepatic Necrosis Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Neonatal Lethality Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Cyanosis Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Decreased T Cell Number Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Abnormal Enzyme/ Coenzyme Level Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Hypoproteinemia Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Hypoalbuminemia Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Abnormal Nucleotide Metabolism Adatm1Mw>/Ada involves: 129S7/SvEvBrd * C57BL/6 7731963 Necrosis Adatm1Vlr>/Ada either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N) 7670465 Abnormal Respiratory Alveoli Morphology Adatm1Vlr>/Ada either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N) 7670465 Atelectasis Adatm1Vlr>/Ada either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N) 7670465 Hepatic Necrosis Adatm1Vlr>/Ada either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N) 7670465 Neonatal Lethality Adatm1Vlr>/Ada either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N) 7670465 Cyanosis Adatm1Vlr>/Ada either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N) 7670465 Extramedullary Hematopoiesis Adatm1Vlr>/Ada either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N) 7670465 Intrahepatic Cholestasis Adatm1Vlr>/Ada either: 129P2/OlaHsd-Ada or (involves: (129P2/OlaHsd * FVB/N) 7670465 Abnormal Dendritic Cell Physiology Adatm1Mw>/Ada involves: 129S7/SvEvBrd 18559975 Increased Dendritic Cell Number Adatm1Mw>/Ada involves: 129S7/SvEvBrd 18559975