Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

TNFRSF13C

External links	Primary Information
MGI:1919299 ENSMUSG00000068105	Gene Symbol	Tnfrsf13c
	Affected Anatomical Systems	hematopoietic system phenotype,homeostasis/metabolism phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:2389403 Tnfrsf13cBcmd1-A/WySnJ QTL B-cell maturation defect 1, A/WySnJ 11003386 MGI:3054891 Tnfrsf13ctm1Mass Targeted (knock-out) targeted mutation 1, Marc Schmidt-Supprian 15294936 MGI:3054873 Tnfrsf13ctm1Msc Targeted (knock-out) targeted mutation 1, Martin L Scott 15294946
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Abnormal Humoral Immune Response Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Decreased IgD Level Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Decreased IgG Level Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Decreased IgM Level Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Decreased B Cell Number Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Absent Marginal Zone B Cells Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Decreased B-2 B Cell Number Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Absent Transitional Stage B Cells Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Decreased IgG1 Level Tnfrsf13ctm1Msc>/Tnfrsf13c involves: 129 * C57BL/6 15294946 Abnormal B Cell Physiology Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 16973390 Decreased IgG Level Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Decreased IgM Level Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Arrested B Cell Differentiation Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Absent Marginal Zone B Cells Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Decreased B-2 B Cell Number Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Decreased Mature B Cell Number Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Decreased IgG1 Level Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Decreased IgG2a Level Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Decreased IgG2b Level Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Decreased IgG3 Level Tnfrsf13ctm1Mass>/Tnfrsf13c C57BL/6-Tnfrsf13c 15294936 Decreased IgG Level Tnfrsf13cBcmd1-A/WySnJ>/Tnfrsf13c A/WySnJ 17073941 Decreased B Cell Proliferation Tnfrsf13cBcmd1-A/WySnJ>/Tnfrsf13c A/WySnJ 17073941 Decreased T Cell Proliferation Tnfrsf13cBcmd1-A/WySnJ>/Tnfrsf13c A/WySnJ 15368291 Abnormal Lymphocyte Physiology Tnfrsf13cBcmd1-A/WySnJ>/Tnfrsf13c A/WySnJ 15368291 Increased Length Of Allograft Survival Tnfrsf13cBcmd1-A/WySnJ>/Tnfrsf13c A/WySnJ 15368291 Decreased Interferon-gamma Secretion Tnfrsf13cBcmd1-A/WySnJ>/Tnfrsf13c A/WySnJ 15368291 Decreased Lymphocyte Cell Number Tnfrsf13ctm1Mass>/Tnfrsf13c involves: C57BL/6 18663224 Decreased Mature B Cell Number Tnfrsf13ctm1Mass>/Tnfrsf13c involves: C57BL/6 18663224