CD3G
Primary Info
Mutation
Mouse studies
DNA sequencing


External links Primary Information
MGI:88333
ENSMUSG00000002033		 Gene Symbol Cd3g
Affected Anatomical Systems hematopoietic system phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id
MGI:2180769 Cd3d/Cd3gtm1Cpt Targeted (knock-out) targeted mutation 1, Cox Terhorst 9763617
MGI:2180763 Cd3gtm1Amk Targeted (knock-out) targeted mutation 1, Ada M Kruisbeek 9524111
MGI:2673301 Cd3gtm2Amk Targeted (knock-out) targeted mutation 2, Ada M Kruisbeek 11160319
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id
Thymus Hypoplasia Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 11160319
Abnormal T Cell Physiology Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 11160319
Abnormal T Cell Differentiation Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 11160319
Abnormal T Cell Activation Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 11160319
Decreased Thymocyte Number Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 10523604
Defective Cytotoxic T Cell Cytolysis Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 11160319
Abnormal T Cell Proliferation Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 11160319
Abnormal CD8-positive T Cell Physiology Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 11160319
Lymph Node Hypoplasia Cd3gtm1Amk>/Cd3g involves: 129P2/OlaHsd 11160319
Thymus Hypoplasia Cd3d/Cd3gtm1Cpt>/Cd3d/Cd3g involves: 129S4/SvJae * C57BL/6 9763617
Arrested T Cell Differentiation Cd3d/Cd3gtm1Cpt>/Cd3d/Cd3g involves: 129S4/SvJae * C57BL/6 9763617
Absent Single-positive T Cells Cd3d/Cd3gtm1Cpt>/Cd3d/Cd3g involves: 129S4/SvJae * C57BL/6 9763617
Absent Gamma-delta T Cells Cd3d/Cd3gtm1Cpt>/Cd3d/Cd3g involves: 129S4/SvJae * C57BL/6 9763617
Spleen Hypoplasia Cd3gtm1.1Cage>/Cd3g B6.129P2-Cd3g 19801521
Decreased Thymocyte Number Cd3gtm1.1Cage>/Cd3g B6.129P2-Cd3g 19801521
Abnormal Response To Infection Cd3gtm1.1Cage>/Cd3g B6.129P2-Cd3g 19801521
Decreased CD8-positive T Cell Number Cd3gtm1.1Cage>/Cd3g B6.129P2-Cd3g 19801521
Increased T Cell Apoptosis Cd3gtm1.1Cage>/Cd3g B6.129P2-Cd3g 19801521