Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

CD79B

External links	Primary Information
MGI:96431 ENSMUSG00000040592	Gene Symbol	Cd79b
	Affected Anatomical Systems	hematopoietic system phenotype,immune system phenotype,no phenotypic analysis
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:3720567 Cd79btm168Mnz Targeted (knock-in) targeted mutation 168, Michel C Nussenzweig MGI:3655464 Cd79btm1Cgn Targeted (Reporter) targeted mutation 1, University of Cologne 16651521 MGI:3722155 Cd79btm1Gzmn Targeted (knock-in) targeted mutation 1, Anna Gazumyan 16818674 MGI:2387024 Cd79btm1Mnz Targeted (knock-out) targeted mutation 1, Michel C Nussenzweig 8602530 MGI:2447121 Cd79btm2.1Mnz Targeted (knock-out) targeted mutation 2.1, Michel C Nussenzweig 11136817 MGI:2447117 Cd79btm2Mnz Targeted (knock-out) targeted mutation 2, Michel C Nussenzweig 11136817 MGI:3768659 Cd79btm3Mnz Targeted (other) targeted mutation 3, Michel C Nussenzweig 15024049
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Abnormal Immune System Physiology Cd79btm1Gzmn>/Cd79b involves: 129/Sv * C57BL/6 16818674 Increased IgD Level Cd79btm1Gzmn>/Cd79b involves: 129/Sv * C57BL/6 16818674 Increased IgM Level Cd79btm1Gzmn>/Cd79b involves: 129/Sv * C57BL/6 16818674 Decreased B-1a Cell Number Cd79btm1Gzmn>/Cd79b involves: 129/Sv * C57BL/6 16818674 Decreased IgG1 Level Cd79btm1Gzmn>/Cd79b involves: 129/Sv * C57BL/6 16818674 Abnormal Immune System Physiology Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Abnormal B Cell Physiology Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Abnormal Immature B Cell Morphology Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Decreased B Cell Number Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Decreased B Cell Proliferation Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Decreased B-1a Cell Number Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Increased Marginal Zone B Cell Number Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Increased Pro-B Cell Number Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Decreased Mature B Cell Number Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Decreased Immature B Cell Number Cd79btm3Mnz>/Cd79b involves: 129/Sv * C57BL/6 15024049 Decreased Mature B Cell Number Cd79btm2.1Mnz>/Cd79b involves: 129 * C57BL/6 11514602 Arrested B Cell Differentiation Cd79btm2.1Mnz>/Cd79b involves: 129/Sv * C57BL/6 11136817 Increased Pro-B Cell Number Cd79btm2.1Mnz>/Cd79b involves: 129/Sv * C57BL/6 11136817 Decreased Transitional Stage B Cell Number Cd79btm2.1Mnz>/Cd79b involves: 129/Sv * C57BL/6 11136817 Decreased Pre-B Cell Number Cd79btm2.1Mnz>/Cd79b involves: 129/Sv * C57BL/6 11136817 Decreased Mature B Cell Number Cd79btm2.1Mnz>/Cd79b involves: 129/Sv * C57BL/6 11136817 Abnormal B Cell Activation Cd79btm2.1Mnz>/Cd79b involves: 129/Sv * C57BL/6 11136817 No Abnormal Phenotype Detected Cd79btm168Mnz>/Cd79b involves: C57BL/6 Abnormal B Cell Differentiation Cd79bm1Ghost>/Cd79b B10.Cg-Ptprc Cd79b H2 19727123 Decreased IgA Level Cd79bm1Ghost>/Cd79b B10.Cg-Ptprc Cd79b H2 19727123 Decreased IgG Level Cd79bm1Ghost>/Cd79b B10.Cg-Ptprc Cd79b H2 19727123 Arrested B Cell Differentiation Cd79bm1Ghost>/Cd79b B10.Cg-Ptprc Cd79b H2 19727123 Absent Peyer's Patches Cd79bm1Ghost>/Cd79b B10.Cg-Ptprc Cd79b H2 19727123 Absent B Cells Cd79bm1Ghost>/Cd79b B10.Cg-Ptprc Cd79b H2 19727123