Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

FOXP3

External links	Primary Information
MGI:1891436 ENSMUSG00000039521	Gene Symbol	Foxp3
	Affected Anatomical Systems	behavior/neurological phenotype,cardiovascular system phenotype,craniofacial phenotype,digestive/alimentary phenotype,endocrine/exocrine gland phenotype,growth/size phenotype,hearing/vestibular/ear phenotype,hematopoietic system phenotype,homeostasis/metabolism phenotype,immune system phenotype,lethality-postnatal,life span-post-weaning/aging,liver/biliary system phenotype,no phenotypic analysis,normal phenotype,renal/urinary system phenotype,reproductive system phenotype,respiratory system phenotype,skin/coat/nails phenotype,vision/eye phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:3817855 Foxp3m1Btlr Chemically induced (ENU) mutation 1, Bruce Beutler MGI:1857034 Foxp3sf Spontaneous scurfy 16590412 MGI:3812203 Foxp3tm1(cre)Saka Targeted (knock-in) targeted mutation 1, Shimon Sakaguchi 18845758 MGI:2654936 Foxp3tm1.1Ayr Targeted (knock-out) targeted mutation 1.1, Alexander Y Rudensky 12612578 MGI:2654935 Foxp3tm1Ayr Targeted (Floxed/Frt) targeted mutation 1, Alexander Y Rudensky 12612578 MGI:3576270 Foxp3tm1Flv Targeted (Reporter) targeted mutation 1, Richard A Flavell 15795373 MGI:3718527 Foxp3tm1Kuch Targeted (Reporter) targeted mutation 1, Vijay K Kuchroo 16648838 MGI:3773675 Foxp3tm1Mal Targeted (Reporter) targeted mutation 1, Bernard Malissen 18209052 MGI:3696705 Foxp3tm1Tch Targeted (knock-out) targeted mutation 1, Talal A Chatila 16275384 MGI:3574964 Foxp3tm2Ayr Targeted (Reporter) targeted mutation 2, Alexander Y Rudensky 15780990 MGI:3700150 Foxp3tm2Flv Targeted (Reporter) targeted mutation 2, Richard A Flavell 17220876 MGI:3699400 Foxp3tm2Tch Targeted (Reporter) targeted mutation 2, Talal A Chatila 17312141 MGI:3698131 Foxp3tm3Ayr Targeted (knock-in) targeted mutation 3, Alexander Y Rudensky 17136045 MGI:3707723 Foxp3tm3Tch Targeted (Reporter) targeted mutation 3, Talal A Chatila 17273171 MGI:3790499 Foxp3tm4(YFP/cre)Ayr Targeted (knock-in) targeted mutation 4, Alexander Y Rudensky 18387831
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Decreased Body Size Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 Scaly Skin Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 Scaly Ears Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 Enlarged Lymph Nodes Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 Enlarged Spleen Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 Abnormal CD4-positive T Cell Morphology Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 Increased Susceptibility To Autoimmune Disorder Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 Skin Inflammation Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 Abnormal CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Morphology Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 12612578 No Abnormal Phenotype Detected Foxp3tm1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ 12612578 No Abnormal Phenotype Detected Foxp3tm2Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ 15780990 No Abnormal Phenotype Detected Foxp3tm2Ayr>/Y involves: 129S1/Sv * 129X1/SvJ 15780990 No Abnormal Phenotype Detected Foxp3tm1Flv>/Foxp3<+ involves: C57BL/6 15795373 Postnatal Lethality Foxp3sf>/0 involves: STOCK MR 16590412 Scaly Skin Foxp3sf>/0 involves: STOCK MR 16590412 Tight Skin Foxp3sf>/0 involves: STOCK MR 16590412 Delayed Eyelid Opening Foxp3sf>/0 involves: STOCK MR 16590412 Decreased Body Size Foxp3sf>/Y involves: STOCK MR 16590412 Postnatal Lethality Foxp3sf>/Y involves: STOCK MR 16590412 Premature Death Foxp3sf>/Y involves: STOCK MR 16590412 Abnormal Male Reproductive System Morphology Foxp3sf>/Y involves: STOCK MR 16590412 Cryptorchism Foxp3sf>/Y involves: STOCK MR Small Testis Foxp3sf>/Y involves: STOCK MR Scaly Skin Foxp3sf>/Y involves: STOCK MR 16590412 Tight Skin Foxp3sf>/Y involves: STOCK MR 16590412 Delayed Eyelid Opening Foxp3sf>/Y involves: STOCK MR 16590412 Small Gonad Foxp3sf>/Y involves: STOCK MR Male Infertility Foxp3sf>/Y involves: STOCK MR 16590412 Absent Scrotum Foxp3sf>/Y involves: STOCK MR Absent Prostate Gland Anterior Lobe Foxp3sf>/Y involves: STOCK MR Absent Seminal Vesicle Foxp3sf>/Y involves: STOCK MR Abnormal Liver Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Respiratory System Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Distended Abdomen Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Decreased Body Size Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Premature Death Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Enlarged Liver Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Enlarged Liver Sinusoidal Spaces Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Lymph Node Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Spleen Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Male Reproductive System Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Epidermal Layer Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal B Cell Physiology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Increased Inflammatory Response Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Hunched Posture Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Red Blood Cell Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Cryptorchism Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Small Testis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Thymus Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Epidermal Hyperplasia Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Dermatitis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Scaly Skin Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Skin Lesions Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Jaundice Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Liver Inflammation Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Scaly Ears Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Small Ears Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Thick Ears Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Anemia Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Increased Leukocyte Cell Number Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Enlarged Heart Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Erythrocyte Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Enlarged Lymph Nodes Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Spleen White Pulp Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Multifocal Hepatic Necrosis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Atrial Thrombosis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Macrophage Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Lymph Node T Cell Domain Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Small Thymus Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Thymus Cortex Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Extramedullary Hematopoiesis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Increased IgG Level Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Increased IgM Level Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Increased Mean Corpuscular Volume Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Lymphocyte Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Anisocytosis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Poikilocytosis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Polychromatophilia Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Cachexia Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Blepharitis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Decreased Hematocrit Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Decreased Hemoglobin Content Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Parakeratosis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Increased Spleen Weight Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Pale Kidney Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Absent Spleen Marginal Zone Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Spleen B Cell Follicle Morphology Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Increased Spleen Red Pulp Amount Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Orthokeratosis Foxp3sf>/Y either: 129Rl.Cg-Foxp3 or (involves: 101/Rl * C3Hf/Rl * STOCK MR) 2053595 Abnormal Liver Morphology Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Decreased Body Size Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Enlarged Liver Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Pale Liver Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Abnormal Spleen Morphology Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Abnormal Male Reproductive System Morphology Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Decreased Body Weight Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Abnormal Red Blood Cell Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Cryptorchism Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Scaly Skin Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Tight Skin Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Gastrointestinal Hemorrhage Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Postnatal Growth Retardation Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Small Gonad Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Small Ears Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Anemia Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Increased Leukocyte Cell Number Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Conjunctivitis Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Abnormal Breathing Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Extramedullary Hematopoiesis Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Abnormal Reticulocyte Morphology Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Absent Scrotum Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Diarrhea Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Lethargy Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Narrow Eye Opening Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Decreased Hematocrit Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Decreased Hemoglobin Content Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Decreased Erythrocyte Cell Number Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Decreased Platelet Cell Number Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Melena Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Short Perineum Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Increased Spleen Weight Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Pale Kidney Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Decreased Megakaryocyte Cell Number Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Intermingled Spleen Red And White Pulp Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Increased Spleen Red Pulp Amount Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Increased Spleen White Pulp Amount Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 Lethality At Weaning Foxp3sf>/Y involves: 101/H * C3H/HeH * STOCK MR 2320565 No Abnormal Phenotype Detected Foxp3tm1Tch>/Foxp3<+ C.129X1-Foxp3 16275384 Postnatal Lethality Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384,17273171 Abnormal Inflammatory Response Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Crypts Of Lieberkuhn Abscesses Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Abnormal Respiratory Mucosa Goblet Cell Morphology Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Dermatitis Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Respiratory System Inflammation Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Anemia Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Leukocyte Cell Number Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Enlarged Spleen Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Monocyte Cell Number Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Activated T Cell Number Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased IgE Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Eosinophil Cell Number Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Lymphocyte Cell Number Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Abnormal Cytokine Secretion Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Decreased Platelet Cell Number Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Abnormal Lymphocyte Physiology Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Absent Regulatory T Cells Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased CD4-positive T Cell Number Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased CD8-positive T Cell Number Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased IgG1 Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Circulating Tumor Necrosis Factor Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Circulating Interferon-gamma Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Circulating Interleukin-10 Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Circulating Interleukin-6 Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Circulating Interleukin-4 Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Increased Circulating Interleukin-5 Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Abnormal Chemokine Level Foxp3tm1Tch>/Y C.129X1-Foxp3 16275384 Postnatal Lethality Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Abnormal Inflammatory Response Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Dermatitis Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Respiratory System Inflammation Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Anemia Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Increased Leukocyte Cell Number Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Increased Monocyte Cell Number Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Increased IgE Level Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Increased Eosinophil Cell Number Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Increased Lymphocyte Cell Number Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Decreased Platelet Cell Number Foxp3tm1Tch>/Y B6.129X1-Foxp3 16275384 Thymus Hypoplasia Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17353370 Dermatitis Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Scaly Skin Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Abnormal T Cell Differentiation Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17353370 Liver Inflammation Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Enlarged Spleen Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Lung Inflammation Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Decreased Double-positive T Cell Number Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17353370 Increased Susceptibility To Autoimmune Disorder Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Lymph Node Inflammation Foxp3tm1.1Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Weight Loss Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Dermatitis Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Liver Inflammation Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Enlarged Spleen Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Conjunctivitis Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Lung Inflammation Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Abnormal Dendritic Cell Physiology Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Decreased T Cell Number Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Cachexia Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Bradykinesia Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Increased Susceptibility To Autoimmune Disorder Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Abnormal CD4-positive T Cell Physiology Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Lymph Node Inflammation Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Increased Dendritic Cell Number Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Increased Sensitivity To Induced Morbidity/mortality Foxp3tm3Ayr>/Foxp3 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Dermatitis Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Scaly Skin Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Liver Inflammation Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Enlarged Spleen Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Lung Inflammation Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Increased Susceptibility To Autoimmune Disorder Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 Lymph Node Inflammation Foxp3tm1.1Ayr>/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 17136045 No Abnormal Phenotype Detected Foxp3tm2Flv>/Foxp3<+ involves: C57BL/6 17220876 Abnormal Immune System Physiology Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Decreased Body Size Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Premature Death Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Scaly Skin Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Male Infertility Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Enlarged Lymph Nodes Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Enlarged Spleen Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Blepharitis Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Abnormal CD4-positive T Cell Physiology Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Increased Autoantibody Level Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Abnormal CD8-positive T Cell Physiology Foxp3tm2Flv>/Y involves: C57BL/6 17220876 Postnatal Lethality Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Thymus Hypoplasia Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Enlarged Lymph Nodes Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Enlarged Spleen Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Abnormal CD4-positive T Cell Morphology Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Abnormal Immune System Organ Morphology Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Colitis Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Increased T Cell Proliferation Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Abnormal CD4-positive T Cell Physiology Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Abnormal Cytokine Secretion Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Abnormal Lymphocyte Physiology Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Abnormal T Cell Subpopulation Ratio Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Abnormal Regulatory T Cell Physiology Foxp3tm3Tch>/Y C.129X1-Foxp3 17273171 Decreased Thymocyte Number Foxp3tm3Tch>/Foxp3<+ C.129X1-Foxp3 17273171 Decreased T Cell Number Foxp3tm3Tch>/Foxp3<+ C.129X1-Foxp3 17273171 Abnormal CD4-positive T Cell Physiology Foxp3tm3Tch>/Foxp3<+ C.129X1-Foxp3 17273171 Increased T Cell Apoptosis Foxp3tm3Tch>/Foxp3<+ C.129X1-Foxp3 17273171 Liver Inflammation Foxp3sf>/? Not Specified 18725525 Lung Inflammation Foxp3sf>/? Not Specified 18725525 Stomach Inflammation Foxp3tm1(cre)Saka>/Y involves: BALB/c 18845758 Increased Autoantibody Level Foxp3tm1(cre)Saka>/Y involves: BALB/c 18845758 Decreased Body Size Foxp3m1Btlr>/Y C57BL/6J-Foxp3 Premature Death Foxp3m1Btlr>/Y C57BL/6J-Foxp3 Alopecia Foxp3m1Btlr>/Y C57BL/6J-Foxp3 Scaly Skin Foxp3m1Btlr>/Y C57BL/6J-Foxp3 Skin Lesions Foxp3m1Btlr>/Y C57BL/6J-Foxp3 Azoospermia Foxp3m1Btlr>/Y C57BL/6J-Foxp3 Dry Skin Foxp3m1Btlr>/Y C57BL/6J-Foxp3 Abnormal Reproductive System Development Foxp3m1Btlr>/Y C57BL/6J-Foxp3 No Abnormal Phenotype Detected Foxp3m1Btlr>/Foxp3<+ C57BL/6J-Foxp3 Abnormal Regulatory T Cell Morphology Foxp3tm7.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Decreased Regulatory T Cell Number Foxp3tm7.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Decreased Regulatory T Cell Number Foxp3tm7.2Ayr>/Foxp3<+ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Decreased Regulatory T Cell Number Foxp3tm6.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Abnormal Gut-associated Lymphoid Tissue Morphology Foxp3tm5.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Abnormal T Cell Differentiation Foxp3tm5.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Abnormal Peyer's Patch Morphology Foxp3tm5.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Increased T Cell Number Foxp3tm5.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Abnormal Mesenteric Lymph Node Morphology Foxp3tm5.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Decreased Regulatory T Cell Number Foxp3tm5.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 Abnormal Intraepithelial T Cell Morphology Foxp3tm5.2Ayr>/Foxp3 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 20072126 No Abnormal Phenotype Detected Foxp3tm8Ayr>/Foxp3<+ B6.129-Foxp3 17220874 Premature Death Foxp3tm8Ayr>/Y B6.129-Foxp3 17220874 Autoimmune Response Foxp3tm8Ayr>/Y B6.129-Foxp3 17220874