Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

IGLL1

External links	Primary Information
MGI:96529 ENSMUSG00000075370	Gene Symbol	Igll1
	Affected Anatomical Systems	hematopoietic system phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:1857189 Igll1tm1Cgn Targeted (knock-out) targeted mutation 1, University of Cologne 1591779 MGI:2677170 Igll1tm1Shim Targeted (knock-out) targeted mutation 1, Takeyuki Shimizu 12055243
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Abnormal Lymphopoiesis Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Spleen Hypoplasia Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Decreased IgG Level Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Abnormal Pre-B Cell Morphology Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Decreased B Cell Number Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779,8808678 Abnormal B Cell Morphology Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Abnormal B-1 B Cell Number Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Increased Pro-B Cell Number Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Decreased IgG1 Level Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Decreased IgG2b Level Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779 Decreased IgG3 Level Igll1tm1Cgn>/Igll1 involves: 129S2/SvPas * C57BL/6 1591779