IL7R
Primary Info
Mutation
Mouse studies
DNA sequencing


External links Primary Information
MGI:96562
ENSMUSG00000003882		 Gene Symbol Il7r
Affected Anatomical Systems hematopoietic system phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id
MGI:3758859 Il7rtm1Abra Targeted (knock-in) targeted mutation 1, Ninan Abraham 17325202
MGI:3038693 Il7rtm1Iku Targeted (knock-out) targeted mutation 1, Koichi Ikuta 8692964
MGI:1857198 Il7rtm1Imx Targeted (knock-out) targeted mutation 1, Immunex 7964471
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id
Thymus Hypoplasia Il7rtm1Imx>/Il7r involves: 129P3/J * 129S7/SvEvBrd 7964471
Spleen Hypoplasia Il7rtm1Imx>/Il7r involves: 129P3/J * 129S7/SvEvBrd 7964471
Arrested B Cell Differentiation Il7rtm1Imx>/Il7r involves: 129P3/J * 129S7/SvEvBrd 7964471
Arrested T Cell Differentiation Il7rtm1Imx>/Il7r involves: 129P3/J * 129S7/SvEvBrd 7964471
Decreased B Cell Number Il7rtm1Imx>/Il7r involves: 129P3/J * 129S7/SvEvBrd 7964471
Decreased T Cell Number Il7rtm1Imx>/Il7r involves: 129P3/J * 129S7/SvEvBrd 7964471
Lymph Node Hypoplasia Il7rtm1Imx>/Il7r involves: 129P3/J * 129S7/SvEvBrd 7964471
Thymus Hypoplasia Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Decreased Bone Marrow Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Abnormal B Cell Differentiation Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Decreased Leukocyte Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Spleen Hypoplasia Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Small Thymus Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Decreased Lymphocyte Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Decreased T Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Increased Double-negative T Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Decreased Double-positive T Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Absent Peyer's Patches Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 9488150
Abnormal T Cell Subpopulation Ratio Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Decreased B-1 B Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Decreased Mature B Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Decreased Immature B Cell Number Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Absent Mature Gamma-delta T Cells Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Abnormal Gamma-delta T Cell Differentiation Il7rtm1Iku>/Il7r involves: 129P2/OlaHsd * C57BL/6J 8692964
Abnormal T Cell Differentiation Il7rtm1Imx>/Il7r B6.129S7-Il7r 17325202
Decreased Thymocyte Number Il7rtm1Imx>/Il7r B6.129S7-Il7r 17325202
Decreased Double-positive T Cell Number Il7rtm1Imx>/Il7r B6.129S7-Il7r 17325202
Abnormal T Cell Differentiation Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Decreased Thymocyte Number Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Decreased B Cell Number Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Abnormal T Cell Proliferation Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Increased Double-positive T Cell Number Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Abnormal CD4-positive T Cell Physiology Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Decreased Memory T Cell Number Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Decreased CD4-positive T Cell Number Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Decreased CD8-positive T Cell Number Il7rtm1Abra>/Il7r B6.129S4-Il7r 17325202
Decreased Thymocyte Number Il7rtm1Imx>/Il7r involves: 129S7/SvEvBrd 11034372