Phenotypes |
Allelic Composition |
Genetic Background |
PubMed Id |
Prenatal Lethality |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
12531011 |
Increased Cellular Sensitivity To Gamma-irradiation |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Decreased Cell Proliferation |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Abnormal Lymphopoiesis |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Abnormal B Cell Differentiation |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Abnormal T Cell Differentiation |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
10911993 |
Small Thymus |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Decreased Thymocyte Number |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
10911993 |
Arrested B Cell Differentiation |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
10911993 |
Arrested T Cell Differentiation |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Abnormal Cell Physiology |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Lethality Throughout Fetal Growth And Development |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Chromosome Breakage |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
12531011 |
Decreased Fetal Size |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac * C57BL/6 |
9823897 |
Abnormal Embryonic Tissue Morphology |
Lig4tm1Icrf>/Lig4 |
involves: 129 |
9889105 |
Prenatal Lethality |
Lig4tm1Icrf>/Lig4 |
involves: 129 |
9889105 |
Increased Neuron Apoptosis |
Lig4tm1Icrf>/Lig4 |
either: (involves: 129P2/OlaHsd) or (involves: 129S1/Sv * 129X1/SvJ) |
11040211,16777961,9889105 |
Lethality Throughout Fetal Growth And Development |
Lig4tm1Icrf>/Lig4 |
either: (involves: 129P2/OlaHsd) or (involves: 129S1/Sv * 129X1/SvJ) |
9889105 |
Chromosome Breakage |
Lig4tm1Fwa>/Lig4<+ |
involves: 129S6/SvEvTac * C57BL/6 |
12531011 |
Decreased Body Size |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Prenatal Lethality |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Decreased Cell Proliferation |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Decreased Bone Marrow Cell Number |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Postnatal Growth Retardation |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Absent CD8-positive T Cells |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
|
Abnormal Proerythroblast Morphology |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Decreased Lymphocyte Cell Number |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Decreased B Cell Number |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Decreased Hematopoietic Stem Cell Number |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Abnormal DNA Repair |
Lig4tiny>/Lig4 |
C57BL/6JApb-Lig4/Apb |
17554302 |
Induced Chromosome Breakage |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
18854157 |
Increased Cellular Sensitivity To Ionizing Radiation |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
18854157 |
Chromosomal Instability |
Lig4tm1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
18854157 |
Abnormal Immune System Physiology |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal Immune System Morphology |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Body Size |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Premature Death |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Increased Cellular Sensitivity To Gamma-irradiation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal Immune System Cell Morphology |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Body Weight |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Reduced Fertility |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal Thymus Morphology |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal Lymphocyte Cell Number |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Postnatal Growth Retardation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal B Cell Differentiation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal T Cell Differentiation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Intestinal Inflammation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Liver Inflammation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Small Spleen |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal T Cell Activation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Immunoglobulin Level |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Small Thymus |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Thymocyte Number |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased IgA Level |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased IgG Level |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased IgM Level |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased B Cell Number |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal Immune System Organ Morphology |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased T Cell Proliferation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Double-negative T Cell Number |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Double-positive T Cell Number |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Thymic Lymphoma |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal Cell Physiology |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Spontaneous Chromosome Breakage |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Medulloblastoma |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Increased Anti-double Stranded DNA Antibody Level |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Increased Anti-chromatin Antibody Level |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal Regulatory T Cell Morphology |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Spleen Weight |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Thymus Weight |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased CD4-positive T Cell Number |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased CD8-positive T Cell Number |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal B Cell Activation |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased IgG2b Level |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased IgG3 Level |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Interferon-gamma Secretion |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Interleukin-13 Secretion |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal T Cell Receptor V(D)J Recombination |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Abnormal T Cell Receptor Beta Chain V(D)J Recombination |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Increased T Cell Apoptosis |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Chromosomal Instability |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Colon Adenocarcinoma |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |
Decreased Splenocyte Number |
Lig4tm2.1Fwa>/Lig4 |
involves: 129S6/SvEvTac |
20133615 |