PTPRC
Primary Info
Mutation
Mouse studies
DNA sequencing


mRNA IDs Primary Information
NM_002838.3,NM_080921.2,NM_080922.2,NM_080923.2 Gene Symbol PTPRC
Protein Name Protein tyrosine phosphatase, receptor type, c
Alternate Names B220, CD45, GP180, LCA, LY5, T200
Gene Locus 1q31-q32

External links
IDR HPRD OMIM Entrez Gene NetPath Reactome PDB HGNC Ensembl Swiss-Prot RefDIC
6 01050 151460 5788 NetPath_M5788 5788 1YGR
1YGU
 9666 ENSG00000081237 P08575 PTPRC

Disease name Characteristic / Associated features Category inheritance type
CD45 deficiency Failure to thrive; chronic diarrhea; respiratory distress; pneumocystosis; recurrent bacterial infections; disseminated BCG infection; normal gamma/delta T cells; reduced number of circulating T cells; normal number of B cells Combined T-cell and B-cell immunodeficiencies Autosomal recessive