| STAT3 deficiency |
Abnormality of the teeth; recurrent Staphylococcus aureus infections; recurrent skin abscesses; lung Abscess; air cyst; bone abnormalities; broad nasal tip; chronic eczema; broad nasal bridge; delayed loss of deciduous teeth; Increased IgE level; Joint hypermobility; hyperkeratotic fingernails due to candida infection; multiple fractures; Candidiasis of nails; osteoporosis; pneumonia, Staphylococcus aureus; scoliosis; thickened skin; Coarse facies; asymmetric face; frontal bossing; mild prognathism; hypertelorism; thickening of the soft tissue of the nose; high-arched palate; reduced resorption of primary tooth roots; recurrent sinopulmonary infections; pneumatocele formation; decreased bone mineral density; craniosynostosis (rare); vertebral body abnormalities; abscesses are cold, lacking erythema, heat, and swelling; recurrent fungal infections |
Other Well-defined Immunodeficiency Syndromes |
Autosomal dominant |