LCK
Primary Info
Mutation
Mouse studies
DNA sequencing


mRNA IDs Primary Information
NM_005356.3 Gene Symbol LCK
Protein Name Lymphocyte-specific protein tyrosine kinase
Alternate Names YT16, p56lck, pp58lck
Gene Locus 1p34.3

External links
IDR HPRD OMIM Entrez Gene NetPath Reactome PDB HGNC Ensembl Swiss-Prot RefDIC
137 01080 153390 3932 NetPath_M3932 3932 1BHF
1BHH
1CWD
1CWE
1FBZ
1H92
1IJR
1KIK
1LCJ
1LCK
1LKK
1LKL
1Q68
1Q69
1QPC
1QPD
1QPE
1QPJ
1X27
2IIM
2OF2
2OF4
2OFU
2OFV
2OG8
3LCK
6524 ENSG00000182866 P06239 LCK

Disease name Characteristic / Associated features Category inheritance type
p56 Lck deficiency Idiopathic CD4-positive T-lymphocytopenia; reduced production of p56lck protein; failure to thrive; opportunistic infections; Absent or severely reduced levels of serum immunoglobulins; T-lymphocyte deficiency Combined T-cell and B-cell immunodeficiencies Autosomal recessive