Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

TNFRSF13B

External links	Primary Information
MGI:1889411 ENSMUSG00000010142	Gene Symbol	Tnfrsf13b
	Affected Anatomical Systems	hematopoietic system phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:3052983 Tnfrsf13btm1Cmac Targeted (knock-out) targeted mutation 1, Charles R Mackay 15240667 MGI:2388136 Tnfrsf13btm1Rjb Targeted (knock-out) targeted mutation 1, Richard J Bram 11371359 MGI:2182823 Tnfrsf13btm1Vmd Targeted (knock-out) targeted mutation 1, Vishva M Dixit 11429549
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Enlarged Spleen Tnfrsf13btm1Cmac>/Tnfrsf13b Not Specified 15240667 Increased B Cell Number Tnfrsf13btm1Cmac>/Tnfrsf13b Not Specified 15240667 Decreased IgA Level Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ * C57BL/6 11371359 Decreased IgM Level Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ * C57BL/6 11371359 Increased B Cell Number Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ * C57BL/6 11371359 Increased B Cell Proliferation Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ * C57BL/6 11371359 Increased Spleen Weight Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ * C57BL/6 11371359 Abnormal B Cell Activation Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ * C57BL/6 11371359 Decreased IgA Level Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ 15630136 Decreased IgE Level Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ 15630136 Abnormal Class Switch Recombination Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ 15630136 Decreased IgG1 Level Tnfrsf13btm1Rjb>/Tnfrsf13b involves: 129X1/SvJ 15630136 Premature Death Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 12594954 Abnormal Spleen Morphology Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Abnormal Immunoglobulin Level Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Kidney Inflammation Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 12594954 Liver Inflammation Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 12594954 Leukemia Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 12594954 Enlarged Lymph Nodes Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549,12594954 Enlarged Spleen Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549,12594954 Abnormal Lymph Node Primary Follicle Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549,12594954 Abnormal Spleen Periarteriolar Lymphoid Sheath Morphology Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549,12594954 Abnormal Peyer's Patch Follicle Morphology Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Increased B Cell Number Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549,12594954 Glomerulonephritis Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 12594954 Increased B Cell Proliferation Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Proteinuria Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 12594954 Increased Anti-double Stranded DNA Antibody Level Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 12594954 Increased Anti-nuclear Antigen Antibody Level Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 12594954 Increased Follicular B Cell Number Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Increased Marginal Zone B Cell Number Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Increased Transitional Stage B Cell Number Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Increased Mature B Cell Number Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Abnormal Spleen Primary B Follicle Morphology Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Increased Spleen White Pulp Amount Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Increased Spleen Germinal Center Size Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549 Increased IgG1 Level Tnfrsf13btm1Vmd>/Tnfrsf13b involves: C57BL/6 11429549