UNG
Primary Info
Mutation
Mouse studies
DNA sequencing


External links Primary Information
MGI:109352
ENSMUSG00000029591		 Gene Symbol Ung
Affected Anatomical Systems cellular phenotype,hematopoietic system phenotype,homeostasis/metabolism phenotype,immune system phenotype,life span-post-weaning/aging,nervous system phenotype,normal phenotype,tumorigenesis
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id
MGI:3046503 Ungtm1Mend Targeted (knock-out) targeted mutation 1, Matthias Endres 15199406
MGI:2182610 Ungtm1Tld Targeted (knock-out) targeted mutation 1, Tomas Lindahl 10912000
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id
No Abnormal Phenotype Detected Ungtm1Tld>/Ung involves: 129/Sv * C57BL/6J 10912000
Premature Death Ungtm1Tld>/Ung Not Specified 12934097
Enlarged Lymph Nodes Ungtm1Tld>/Ung Not Specified 12934097
Enlarged Spleen Ungtm1Tld>/Ung Not Specified 12934097
Spleen Hyperplasia Ungtm1Tld>/Ung Not Specified 12934097
Lymphoid Hyperplasia Ungtm1Tld>/Ung Not Specified 12934097
B Cell Derived Lymphoma Ungtm1Tld>/Ung Not Specified 12934097
Enlarged Thymus Ungtm1Tld>/Ung Not Specified 12934097
Increased IgM Level Ungtm1Tld>/Ung Not Specified 12401169
Abnormal Class Switch Recombination Ungtm1Tld>/Ung Not Specified 12401169
Decreased IgG3 Level Ungtm1Tld>/Ung Not Specified 12401169
Increased Susceptibility To Ischemic Brain Injury Ungtm1Mend>/Ung involves: 129S4/SvJae * BALB/c 15199406
Increased Cellular Sensitivity To Oxidative Stress Ungtm1Mend>/Ung involves: 129S4/SvJae * BALB/c 15199406
Abnormal Somatic Hypermutation Frequency Ungtm1Tld>/Ung involves: 129P2/OlaHsd 19901081