CD19
Primary Info
Mutation
Mouse studies
DNA sequencing


External links Primary Information
MGI:88319
ENSMUSG00000030724		 Gene Symbol Cd19
Affected Anatomical Systems cellular phenotype,digestive/alimentary phenotype,hematopoietic system phenotype,homeostasis/metabolism phenotype,immune system phenotype,liver/biliary system phenotype,normal phenotype,renal/urinary system phenotype,tumorigenesis
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id
MGI:1931143 Cd19tm1(cre)Cgn Targeted (knock-in) targeted mutation 1, University of Cologne 7543183
MGI:3584432 Cd19tm1(cre)Thr Targeted (knock-in) targeted mutation 1, Terence H Rabbitts 14645513
MGI:2180685 Cd19tm1Tft Targeted (knock-out) targeted mutation 1, Thomas F Tedder 7542548
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id
Abnormal B Cell Physiology Cd19tm1(cre)Cgn>/Cd19 involves: 129P2/OlaHsd 7543183
Abnormal Immunoglobulin Level Cd19tm1(cre)Cgn>/Cd19 involves: 129P2/OlaHsd 7543183
Abnormal B Cell Differentiation Cd19tm1(cre)Cgn>/Cd19 involves: 129P2/OlaHsd 7543183
Decreased IgM Level Cd19tm1(cre)Cgn>/Cd19 involves: 129P2/OlaHsd 7543183
Decreased B-1 B Cell Number Cd19tm1(cre)Cgn>/Cd19 involves: 129P2/OlaHsd 7543183
Absent Spleen Germinal Center Cd19tm1(cre)Cgn>/Cd19 involves: 129P2/OlaHsd 7543183
Abnormal B Cell Physiology Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased IgA Level Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased IgM Level Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased B Cell Number Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased B Cell Proliferation Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased B-1 B Cell Number Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased IgG1 Level Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased IgG2a Level Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased IgG2b Level Cd19tm1Tft>/Cd19 Not Specified 7542548
Decreased IgG3 Level Cd19tm1Tft>/Cd19 Not Specified 7542548