CYBB
Primary Info
Mutation
Mouse studies
DNA sequencing


External links Primary Information
MGI:88574
ENSMUSG00000015340		 Gene Symbol Cybb
Affected Anatomical Systems digestive/alimentary phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id
MGI:1857284 Cybbtm1Din Targeted (knock-out) targeted mutation 1, Mary C Dinauer 7719350
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id
Abnormal Immune System Physiology Cybbtm1Din>/Y involves: 129S/SvEv * C57BL/6 7719350
Increased Inflammatory Response Cybbtm1Din>/Y involves: 129S/SvEv * C57BL/6 7719350
Increased Susceptibility To Infection Cybbtm1Din>/Y involves: 129S/SvEv * C57BL/6 7719350
Increased Susceptibility To Bacterial Infection Cybbtm1Din>/Y involves: 129S/SvEv * C57BL/6 7719350
Abnormal Macrophage Physiology Cybbtm1Din>/Y involves: 129S/SvEv * C57BL/6 7719350
Abnormal Neutrophil Physiology Cybbtm1Din>/Y involves: 129S/SvEv * C57BL/6 7719350
Abnormal Intestinal Mucosa Morphology Cybbtm1Din>/Cybb involves: 129S/SvEv * C57BL/6 10982764
Abnormal Gastric Mucosa Morphology Cybbtm1Din>/Cybb involves: 129S/SvEv * C57BL/6 10982764
Abnormal Spatial Learning Cybbtm1Din>/Cybb B6.129S-Cybb 16847341
Impaired Coordination Cybbtm1Din>/Cybb B6.129S-Cybb 16847341
Reduced Long Term Potentiation Cybbtm1Din>/Cybb B6.129S-Cybb 16847341
Decreased Vertical Activity Cybbtm1Din>/Cybb B6.129S-Cybb 16847341
Decreased Post-tetanic Potentiation Cybbtm1Din>/Cybb B6.129S-Cybb 16847341