RAPID Lite

TNFRSF13B

mRNA IDs	Primary Information
NM_012452.2	Gene Symbol	TNFRSF13B
	Protein Name	Tumor necrosis factor receptor superfamily, member 13b
	Alternate Names	CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B
	Gene Locus	17p11.2

External links

IDR	HPRD	OMIM	Entrez Gene	NetPath	Reactome	PDB	HGNC	Ensembl	Swiss-Prot	RefDIC
153	05365	604907	23495			1XU1 1XUT	18153	ENSG00000108516	O14836	TNFRSF13B

Disease name	Characteristic / Associated features	Category	inheritance type
TACI deficiency	Chronic sinusitis; recurrent otitis media; conjunctivitis; bronchiectasis; recurrent pneumonia; hepatomegaly; splenomegaly; chronic enteritis; diarrhea; meningitis; recurrent bacterial infections; lymphadenopathy; decreased IgG level; defective antibody production; increased number of B cells; variable degree of T cell dysfunction; lymph nodes show florid reactive follicular hyperplasia and marked paracortical expansion with immunoblasts and plasma cells; autoimmune disease; lymphoma; markedly reduced IgA levels; markedly reduced IgG levels; reduced IgM levels; Abnormal immunoglobulin level; Absent specific antibody response; Defective B cell differentiation; low numbers of CD27+ memory B cells	Predominantly antibody deficiencies	Autosomal recessive / Autosomal dominant
TACI deficiency	Recurrent sinopulmonary infections; gastrointestinal infections; autoimmune disease	Predominantly antibody deficiencies	-
-	Bacterial infections; Opportunistic Infection; Autoimmune Disease; decreased number of pro-B cells	Predominantly antibody deficiencies	-