| Familial hemophagocytic lymphohistiocytosis 3 |
Severe inflammation; high fever; irritability; generalized aches and pains; edema; viral disease; skin rash; lymphadenopathy; hepatosplenomegaly; pancytopenia; hypertriglyceridemia; hypofibrinogenemia; splenomegaly; cytopenia; hyperferritinemia; hemophagocytosis; central nervous system symptoms; decreased NK cell activity; decreased CTL activity; abnormality of coagulation; macrophage activation syndrome; defective anti-CD3-driven cytotoxic T-cell activity |
Diseases of Immune Dysregulation |
Autosomal recessive |