mRNA IDs | Primary Information | |
NM_003362.2,NM_080911.1 | Gene Symbol | UNG |
Protein Name | Uracil-dna glycosylase | |
Alternate Names | DGU, DKFZp781L1143, HIGM4, UDG, UNG1, UNG15, UNG2 | |
Gene Locus | 12q23-q24.1 |
External links | ||||||||||||||||||||||||
|
Disease name | Characteristic / Associated features | Category | inheritance type |
UNG deficiency | Increased susceptibility to bacterial infections; neutropenia; thrombocytopenia; hemolytic anemia; chronic epididymitis; lymph node enlargement; enlarged germinal centers; lymphoid hyperplasia; increased IgM level; decreased IgA; decreased IgG; decreased IgE; impaired Ig class switch recombination (CSR); normal B-cell (CD19+) count | Predominantly antibody deficiencies | Autosomal recessive |