Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

G6PC3

External links	Primary Information
MGI:1915651 ENSMUSG00000034793	Gene Symbol	G6pc3
	Affected Anatomical Systems	digestive/alimentary phenotype,endocrine/exocrine gland phenotype,growth/size phenotype,hematopoietic system phenotype,homeostasis/metabolism phenotype,immune system phenotype,life span-post-weaning/aging
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:3710232 G6pc3tm1Jyc Targeted (knock-out) targeted mutation 1, Janice Y Chou 17318259 MGI:3697438 G6pc3tm1Rmob Targeted (knock-out) targeted mutation 1, Richard M O'Brien 17023421
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Decreased Body Length G6pc3tm1Rmob>/G6pc3 involves: 129S5/SvEvBrd * C57BL/6J 17023421 Decreased Body Weight G6pc3tm1Rmob>/G6pc3 involves: 129S5/SvEvBrd * C57BL/6J 17023421 Postnatal Growth Retardation G6pc3tm1Rmob>/G6pc3 involves: 129S5/SvEvBrd * C57BL/6J 17023421 Increased Circulating Glucagon Level G6pc3tm1Rmob>/G6pc3 involves: 129S5/SvEvBrd * C57BL/6J 17023421 Decreased Circulating Cholesterol Level G6pc3tm1Rmob>/G6pc3 involves: 129S5/SvEvBrd * C57BL/6J 17023421 Increased Pancreatic Alpha Cell Number G6pc3tm1Rmob>/G6pc3 involves: 129S5/SvEvBrd * C57BL/6J 17023421 Increased Granulocyte Number G6pc3tm1Jyc>/G6pc3 involves: 129S4/SvJae * C57BL/6 17318259 Increased Susceptibility To Bacterial Infection G6pc3tm1Jyc>/G6pc3 involves: 129S4/SvJae * C57BL/6 17318259 Abnormal Neutrophil Physiology G6pc3tm1Jyc>/G6pc3 involves: 129S4/SvJae * C57BL/6 17318259 Decreased Neutrophil Cell Number G6pc3tm1Jyc>/G6pc3 involves: 129S4/SvJae * C57BL/6 17318259 Impaired Granulocyte Bactericidal Activity G6pc3tm1Jyc>/G6pc3 involves: 129S4/SvJae * C57BL/6 17318259 Increased Sensitivity To Induced Morbidity/mortality G6pc3tm1Jyc>/G6pc3 involves: 129S4/SvJae * C57BL/6 17318259