Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

CARD9

External links	Primary Information
MGI:2685628 ENSMUSG00000026928	Gene Symbol	Card9
	Affected Anatomical Systems	homeostasis/metabolism phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:3663486 Card9tm1Jrld Targeted (knock-out) targeted mutation 1, Jurgen Ruland 16862125 MGI:3715521 Card9tm1Tks Targeted (knock-out) targeted mutation 1, Takashi Saito 17486093 MGI:3698412 Card9tm1Xlin Targeted (knock-out) targeted mutation 1, Xin Lin 17187069
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Abnormal Dendritic Cell Physiology Card9tm1Jrld>/Card9 involves: 129P2/OlaHsd 16862125 Increased Susceptibility To Fungal Infection Card9tm1Jrld>/Card9 involves: 129P2/OlaHsd 16862125 Abnormal Innate Immunity Card9tm1Xlin>/Card9 involves: 129/Sv * C57BL/6 17187069 Increased Susceptibility To Bacterial Infection Card9tm1Xlin>/Card9 involves: 129/Sv * C57BL/6 17187069 Abnormal Macrophage Physiology Card9tm1Xlin>/Card9 involves: 129/Sv * C57BL/6 17187069 Abnormal Cytokine Level Card9tm1Xlin>/Card9 involves: 129/Sv * C57BL/6 17187069 Increased Susceptibility To Bacterial Infection Card9tm1Tks>/Card9 B6.129-Card9 17486093 Abnormal Macrophage Physiology Card9tm1Tks>/Card9 B6.129-Card9 17486093,18776906 Abnormal Dendritic Cell Physiology Card9tm1Tks>/Card9 B6.129-Card9 17486093 Abnormal Cytokine Secretion Card9tm1Tks>/Card9 B6.129-Card9 17486093 Abnormal Chemokine Secretion Card9tm1Tks>/Card9 B6.129-Card9 18776906