Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

FAS

External links	Primary Information
MGI:95484 ENSMUSG00000024778	Gene Symbol	Fas
	Affected Anatomical Systems	behavior/neurological phenotype,cardiovascular system phenotype,cellular phenotype,craniofacial phenotype,digestive/alimentary phenotype,endocrine/exocrine gland phenotype,growth/size phenotype,hearing/vestibular/ear phenotype,hematopoietic system phenotype,homeostasis/metabolism phenotype,immune system phenotype,lethality-prenatal/perinatal,life span-post-weaning/aging,limbs/digits/tail phenotype,liver/biliary system phenotype,muscle phenotype,nervous system phenotype,pigmentation phenotype,renal/urinary system phenotype,reproductive system phenotype,respiratory system phenotype,skeleton phenotype,skin/coat/nails phenotype,touch/vibrissae phenotype,tumorigenesis,vision/eye phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:1856335 Faslpr-cg Spontaneous lymphoproliferation complementing gld 2406366 MGI:1856334 Faslpr Spontaneous lymphoproliferation MGI:3690544 Fastm1.1Cgn Targeted (knock-out) targeted mutation 1.1, University of Cologne 15148335 MGI:3589104 Fastm1Ach Targeted (Floxed/Frt) targeted mutation 1, Alexander Chervonsky 17509906 MGI:3690464 Fastm1Cgn Targeted (Floxed/Frt) targeted mutation 1, University of Cologne 15148335 MGI:3045400 Fastm1Dlo Targeted (knock-out) targeted mutation 1, Dennis Y Loh 8671629 MGI:1861923 Fastm1Osa Targeted (Reporter) targeted mutation 1, Osaka University Medical School 7581453 MGI:2679555 Fastm1Vbo Targeted (Floxed/Frt) targeted mutation 1, Harald von Boehmer 14530378
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Premature Death Faslpr-cg>/Fas CBA/KlJms-Fas/J 2406366 Hypersensitivity Faslpr-cg>/Fas CBA/KlJms-Fas/J 2302830,2406366 Abnormal Lymph Organ Size Faslpr-cg>/Fas CBA/KlJms-Fas/J 2406366 Abnormal T Cell Differentiation Faslpr-cg>/Fas CBA/KlJms-Fas/J 2406366 Autoimmune Response Faslpr-cg>/Fas CBA/KlJms-Fas/J 2302830,2406366 Enlarged Lymph Nodes Faslpr-cg>/Fas CBA/KlJms-Fas/J 2302830,2406366 Enlarged Spleen Faslpr-cg>/Fas CBA/KlJms-Fas/J 2406366 Increased Immunoglobulin Level Faslpr-cg>/Fas CBA/KlJms-Fas/J 2406366 Increased IgG Level Faslpr-cg>/Fas CBA/KlJms-Fas/J 2302830,2406366 Increased IgM Level Faslpr-cg>/Fas CBA/KlJms-Fas/J 2302830,2406366 Increased Autoantibody Level Faslpr-cg>/Fas CBA/KlJms-Fas/J 2302830 Increased Anti-nuclear Antigen Antibody Level Faslpr-cg>/Fas CBA/KlJms-Fas/J 2406366 Increased Spleen Weight Faslpr-cg>/Fas CBA/KlJms-Fas/J 2302830 Premature Death Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453 Hypersensitivity Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453,8700897 Abnormal Hepatocyte Morphology Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453 Abnormal Lymph Organ Size Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453 Abnormal T Cell Clonal Deletion Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased Leukocyte Cell Number Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Enlarged Lymph Nodes Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453,8700897 Enlarged Spleen Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453,8700897 Lymphoid Hyperplasia Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453 Increased IgG Level Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased Lymphocyte Cell Number Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453,8700897 Increased B Cell Number Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased Susceptibility To Parasitic Infection Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 12594834 Liver Hyperplasia Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 7581453 Increased Autoantibody Level Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased Anti-double Stranded DNA Antibody Level Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased Anti-single Stranded DNA Antibody Level Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased IgG1 Level Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased IgG2a Level Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased IgG2b Level Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Increased IgG3 Level Fastm1Osa>/Fas involves: 129P2/OlaHsd * C57BL/6 8700897 Abnormal Cardiovascular System Physiology Faslpr>/Fas MRL/Mp-Fas 309911 Abnormal Immune System Physiology Faslpr>/Fas MRL/Mp-Fas Abnormal Lacrimal Gland Morphology Faslpr>/Fas MRL/Mp-Fas 8163351 Abnormal Thyroid Gland Morphology Faslpr>/Fas MRL/Mp-Fas 7628400 Abnormal Gland Morphology Faslpr>/Fas MRL/Mp-Fas 8163351 Premature Death Faslpr>/Fas MRL/Mp-Fas 309911 Abnormal Lymph Node Morphology Faslpr>/Fas MRL/Mp-Fas 309911 Type III Hypersensitivity Reaction Faslpr>/Fas MRL/Mp-Fas Skin Lesions Faslpr>/Fas MRL/Mp-Fas Abnormal T Cell Physiology Faslpr>/Fas MRL/Mp-Fas 3009614 Salivary Gland Inflammation Faslpr>/Fas MRL/Mp-Fas 7957574,8163351 Vascular Inflammation Faslpr>/Fas MRL/Mp-Fas Enlarged Lymph Nodes Faslpr>/Fas MRL/Mp-Fas 309911,762500 Enlarged Spleen Faslpr>/Fas MRL/Mp-Fas Increased Immunoglobulin Level Faslpr>/Fas MRL/Mp-Fas 6444324 Enlarged Thymus Faslpr>/Fas MRL/Mp-Fas Abnormal Thymus Cortex Morphology Faslpr>/Fas MRL/Mp-Fas Abnormal Thymus Medulla Morphology Faslpr>/Fas MRL/Mp-Fas Increased IgA Level Faslpr>/Fas MRL/Mp-Fas Increased IgG Level Faslpr>/Fas MRL/Mp-Fas 309911 Increased IgM Level Faslpr>/Fas MRL/Mp-Fas Abnormal Immune System Organ Morphology Faslpr>/Fas MRL/Mp-Fas Glomerulonephritis Faslpr>/Fas MRL/Mp-Fas 309911 Abnormal Cytotoxic T Cell Physiology Faslpr>/Fas MRL/Mp-Fas 6610701 Abnormal T Cell Proliferation Faslpr>/Fas MRL/Mp-Fas 3009614 Proteinuria Faslpr>/Fas MRL/Mp-Fas Abnormal Renal Glomerulus Morphology Faslpr>/Fas MRL/Mp-Fas 309911 Increased Susceptibility To Autoimmune Disorder Faslpr>/Fas MRL/Mp-Fas 762500 Abnormal Circulating Protein Level Faslpr>/Fas MRL/Mp-Fas 309911 Abnormal T-helper 2 Physiology Faslpr>/Fas MRL/Mp-Fas 6444324 Joint Swelling Faslpr>/Fas MRL/Mp-Fas 309911 Hyperalbuminemia Faslpr>/Fas MRL/Mp-Fas Increased Circulating Total Protein Level Faslpr>/Fas MRL/Mp-Fas Thyroid Inflammation Faslpr>/Fas MRL/Mp-Fas 7628400 Thymus Atrophy Faslpr>/Fas MRL/Mp-Fas 309911 Increased Autoantibody Level Faslpr>/Fas MRL/Mp-Fas Abnormal Submandibular Gland Morphology Faslpr>/Fas MRL/Mp-Fas 8163351 Abnormal Coronary Artery Morphology Faslpr>/Fas MRL/Mp-Fas 309911 Abnormal Thyroid Follicle Morphology Faslpr>/Fas MRL/Mp-Fas 7628400 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas MRL/Mp-Fas 12486097,309911,6444324 Increased Anti-single Stranded DNA Antibody Level Faslpr>/Fas MRL/Mp-Fas 309911 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas MRL/Mp-Fas 309911 Increased Anti-erythrocyte Antigen Antibody Level Faslpr>/Fas MRL/Mp-Fas 309911 Abnormal B Cell Morphology Faslpr>/Fas MRL/Mp-Fas 762500 Increased Thymus Weight Faslpr>/Fas MRL/Mp-Fas Abnormal T Cell Morphology Faslpr>/Fas MRL/Mp-Fas 3009614,6602708,6815273,762500 Lymph Node Hyperplasia Faslpr>/Fas MRL/Mp-Fas 309911 Enlarged Peyer's Patches Faslpr>/Fas MRL/Mp-Fas Abnormal Marginal Zone B Cell Morphology Faslpr>/Fas MRL/Mp-Fas 12486097 Increased IgG1 Level Faslpr>/Fas MRL/Mp-Fas Increased IgG2a Level Faslpr>/Fas MRL/Mp-Fas Increased IgG2b Level Faslpr>/Fas MRL/Mp-Fas Decreased Interleukin-2 Secretion Faslpr>/Fas MRL/Mp-Fas 6610701,6975351 Abnormal Interleukin Level Faslpr>/Fas MRL/Mp-Fas 3009614 Abnormal B Cell Receptor Editing Faslpr>/Fas MRL/Mp-Fas 12486097 Abnormal Lymph Node Cell Ratio Faslpr>/Fas MRL/Mp-Fas 6444324 Abnormal Thymus Involution Fastm1Dlo>/Fas involves: 129P2/OlaHsd * C57BL/6 15192051 Abnormal Apoptosis Fastm1Dlo>/Fas involves: 129P2/OlaHsd * C57BL/6 15192051 Enlarged Lymph Nodes Fastm1Dlo>/Fas involves: 129P2/OlaHsd * C57BL/6 8671629 Enlarged Spleen Fastm1Dlo>/Fas involves: 129P2/OlaHsd * C57BL/6 8671629 Increased Immunoglobulin Level Fastm1Dlo>/Fas involves: 129P2/OlaHsd * C57BL/6 8671629 Increased Body Weight Faslpr>/Fas MRL/Mp-Fas atms 12787314 Increased Tumor Incidence Faslpr>/Fas MRL/Mp-Fas atms 12787314 Ruffled Hair Faslpr>/Fas MRL/Mp-Fas atms 12787314 Enlarged Lymph Nodes Faslpr>/Fas MRL/Mp-Fas atms 12787314 Enlarged Spleen Faslpr>/Fas MRL/Mp-Fas atms 12787314 Enlarged Thymus Faslpr>/Fas MRL/Mp-Fas atms 12787314 Decreased Susceptibility To Autoimmune Diabetes Faslpr>/Fas NOD.MRL(B6)-Fas 10946317 Premature Death Faslpr>/Fas MRL/MpJ-Fas/J 6609979 Abnormal Kidney Physiology Faslpr>/Fas MRL/MpJ-Fas/J 17142777 Abnormal Spatial Learning Faslpr>/Fas MRL/MpJ-Fas/J 8496852 Abnormal Lymph Node Morphology Faslpr>/Fas MRL/MpJ-Fas/J 6609979 Impaired Coordination Faslpr>/Fas MRL/MpJ-Fas/J 8496852 Abnormal Immunoglobulin Level Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Enlarged Lymph Nodes Faslpr>/Fas MRL/MpJ-Fas/J 6609979 Increased Immunoglobulin Level Faslpr>/Fas MRL/MpJ-Fas/J 17073941,6609979 Conjunctivitis Faslpr>/Fas MRL/MpJ-Fas/J 17208228 Vasculitis Faslpr>/Fas MRL/MpJ-Fas/J 17142777 Abnormal Stria Vascularis Faslpr>/Fas MRL/MpJ-Fas/J 1416659 Increased Neutrophil Cell Number Faslpr>/Fas MRL/MpJ-Fas/J 17142777 Cortical Renal Glomerulopathies Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Decreased IgG Level Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Glomerulonephritis Faslpr>/Fas MRL/MpJ-Fas/J 17073941,17142777,6609979 Proteinuria Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Abnormal Cardiac Muscle Morphology Faslpr>/Fas MRL/MpJ-Fas/J 8496852 Abnormal Renal Glomerulus Morphology Faslpr>/Fas MRL/MpJ-Fas/J 17142777,6609979 Abnormal Mesangial Cell Faslpr>/Fas MRL/MpJ-Fas/J 17142777 Albuminuria Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Abnormal Enzyme/coenzyme Activity Faslpr>/Fas MRL/MpJ-Fas/J 12974753 CNS Inflammation Faslpr>/Fas MRL/MpJ-Fas/J 8496852 Increased Autoantibody Level Faslpr>/Fas MRL/MpJ-Fas/J 8496852 Abnormal Strial Intermediate Cells Faslpr>/Fas MRL/MpJ-Fas/J 1416659 Abnormal Conjunctival Epithelium Faslpr>/Fas MRL/MpJ-Fas/J 17208228 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas MRL/MpJ-Fas/J 17073941,6609979 Decreased Brainstem Auditory Evoked Potential Faslpr>/Fas MRL/MpJ-Fas/J 1416659 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas MRL/MpJ-Fas/J 11067882,6609979,8496852 Increased Plasma Cell Number Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Decreased Marginal Zone B Cell Number Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Decreased Transitional Stage B Cell Number Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Decreased Mature B Cell Number Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Decreased Immature B Cell Number Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Decreased Spleen Germinal Center Number Faslpr>/Fas MRL/MpJ-Fas/J 17073941 Decreased Susceptibility To Autoimmune Diabetes Faslpr>/Fas NOD.MRL-Fas 9094710 Abnormal Immune System Morphology Fastm1.1Cgn>/Fas involves: C57BL/6 15148335 Enlarged Lymph Nodes Fastm1.1Cgn>/Fas involves: C57BL/6 15148335 Enlarged Spleen Fastm1.1Cgn>/Fas involves: C57BL/6 15148335 Abnormal Immune System Morphology Faslpr>/Fas involves: C57BL/6 * MRL 15148335 Enlarged Lymph Nodes Faslpr>/Fas involves: C57BL/6 * MRL 15148335 Enlarged Spleen Faslpr>/Fas involves: C57BL/6 * MRL 15148335 Autoimmune Response Faslpr>/Fas involves: C3H * MRL/Mp 2708160 Abnormal Stria Vascularis Faslpr>/Fas involves: C3H * MRL/Mp 2708160,8793508 Increased Susceptibility To Type III Hypersensitivity Reaction Faslpr>/Fas involves: C3H * MRL/Mp 8793508 Abnormal Stria Vascularis Vasculature Morphology Faslpr>/Fas involves: C3H * MRL/Mp 8793508 Decreased Brainstem Auditory Evoked Potential Faslpr>/Fas involves: C3H * MRL/Mp 2708160,8793508 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas involves: C3H * MRL/Mp 8793508 Increased Susceptibility To Systemic Lupus Erythematosus Faslpr>/Fas involves: C3H * MRL/Mp 8793508 Increased Spleen Weight Faslpr>/Fas involves: C3H * MRL/Mp 8793508 Abnormal Kidney Morphology Faslpr>/Fas B6.MRL-Fas/J 18275831 Abnormal Hepatocyte Morphology Faslpr>/Fas B6.MRL-Fas/J 16118350 Abnormal Liver Physiology Faslpr>/Fas B6.MRL-Fas/J 10878371,16118350 Brain Inflammation Faslpr>/Fas B6.MRL-Fas/J 9736651 Increased Susceptibility To Bacterial Infection Faslpr>/Fas B6.MRL-Fas/J 15980239 Increased Susceptibility To Viral Infection Faslpr>/Fas B6.MRL-Fas/J 9736651 Enlarged Lymph Nodes Faslpr>/Fas B6.MRL-Fas/J 11035071 Focal Hepatic Necrosis Faslpr>/Fas B6.MRL-Fas/J 16118350 Demyelination Faslpr>/Fas B6.MRL-Fas/J 9736651 CNS Inflammation Faslpr>/Fas B6.MRL-Fas/J 9736651 Increased Autoantibody Level Faslpr>/Fas B6.MRL-Fas/J 18275831 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas B6.MRL-Fas/J 18275831 Increased Anti-single Stranded DNA Antibody Level Faslpr>/Fas B6.MRL-Fas/J 18275831 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas B6.MRL-Fas/J 18275831 Increased Anti-histone Antibody Level Faslpr>/Fas B6.MRL-Fas/J 18275831 Lymph Node Hyperplasia Faslpr>/Fas B6.MRL-Fas/J 18275831 Increased Follicular B Cell Number Faslpr>/Fas B6.MRL-Fas/J 18275831 Increased Marginal Zone B Cell Number Faslpr>/Fas B6.MRL-Fas/J 18275831 Increased Transitional Stage B Cell Number Faslpr>/Fas B6.MRL-Fas/J 18275831 Increased Immature B Cell Number Faslpr>/Fas B6.MRL-Fas/J 18275831 Decreased B Cell Apoptosis Faslpr>/Fas B6.MRL-Fas/J 16118350 Abnormal Splenic Cell Ratio Faslpr>/Fas B6.MRL-Fas/J 18275831 Decreased Hepatocyte Apoptosis Faslpr>/Fas B6.MRL-Fas/J 16118350 Increased Splenocyte Number Faslpr>/Fas B6.MRL-Fas/J 18275831 Enlarged Lymph Nodes Faslpr>/Fas MRL-Fas 16365433 Increased Immunoglobulin Level Faslpr>/Fas MRL-Fas 6444324 Vasculitis Faslpr>/Fas MRL-Fas 16365433 Increased IgG Level Faslpr>/Fas MRL-Fas 16365433 Increased IgM Level Faslpr>/Fas MRL-Fas 16365433 Glomerulonephritis Faslpr>/Fas MRL-Fas 16365433 Abnormal T-helper 2 Physiology Faslpr>/Fas MRL-Fas 6444324 Increased Blood Urea Nitrogen Level Faslpr>/Fas MRL-Fas 16365433 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas MRL-Fas 16365433 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas MRL-Fas 16365433 Increased Spleen Weight Faslpr>/Fas MRL-Fas 16365433 Premature Death Faslpr>/Fas MRL.Cg-Irf1 Fas 16541466 Abnormal Skin Condition Faslpr>/Fas MRL.Cg-Irf1 Fas 16541466 Epidermal Necrosis Faslpr>/Fas MRL.Cg-Irf1 Fas 16541466 Skin Lesions Faslpr>/Fas MRL.Cg-Irf1 Fas 16541466 Glomerulonephritis Faslpr>/Fas MRL.Cg-Irf1 Fas 16541466 Proteinuria Faslpr>/Fas MRL.Cg-Irf1 Fas 16541466 Kidney Failure Faslpr>/Fas MRL.Cg-Irf1 Fas 16541466 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas MRL.Cg-Irf1 Fas 16541466 Premature Death Faslpr>/Fas C3.MRL-Fas/J 6609979 Abnormal Lymph Node Morphology Faslpr>/Fas C3.MRL-Fas/J 6609979 Enlarged Lymph Nodes Faslpr>/Fas C3.MRL-Fas/J 6609979 Increased Immunoglobulin Level Faslpr>/Fas C3.MRL-Fas/J 6609979 Abnormal Airway Responsiveness Faslpr>/Fas C3.MRL-Fas/J 11590380 Decreased Eosinophil Cell Number Faslpr>/Fas C3.MRL-Fas/J 11590380 Glomerulonephritis Faslpr>/Fas C3.MRL-Fas/J 6609979 Abnormal Renal Glomerulus Morphology Faslpr>/Fas C3.MRL-Fas/J 6609979 Increased Apoptosis Faslpr>/Fas C3.MRL-Fas/J 11590380 Increased Autoantibody Level Faslpr>/Fas C3.MRL-Fas/J 6609979 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas C3.MRL-Fas/J 6609979 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas C3.MRL-Fas/J 6609979 Abnormal T Cell Morphology Faslpr>/Fas C3.MRL-Fas/J 6609979 Lymph Node Hyperplasia Faslpr>/Fas C3.MRL-Fas/J 6609979 Abnormal B Cell Activation Faslpr>/Fas C3.MRL-Fas/J 6609979 Decreased Interleukin-2 Secretion Faslpr>/Fas C3.MRL-Fas/J 6609979 Premature Death Faslpr>/Fas B6.MRL-Fas 16818796,6609979,6975351 Abnormal Lymph Node Morphology Faslpr>/Fas B6.MRL-Fas 6609979 Enlarged Lymph Nodes Faslpr>/Fas B6.MRL-Fas 16818796,6609979,6975351 Enlarged Spleen Faslpr>/Fas B6.MRL-Fas 16818796 Increased Immunoglobulin Level Faslpr>/Fas B6.MRL-Fas 6609979 Glomerulonephritis Faslpr>/Fas B6.MRL-Fas 16818796,6609979 Increased Double-negative T Cell Number Faslpr>/Fas B6.MRL-Fas 16818796 Abnormal Renal Glomerulus Morphology Faslpr>/Fas B6.MRL-Fas 6609979 Increased Autoantibody Level Faslpr>/Fas B6.MRL-Fas 16818796,6609979 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas B6.MRL-Fas 6609979 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas B6.MRL-Fas 16818796,6609979,6975351 Decreased Interleukin-2 Secretion Faslpr>/Fas B6.MRL-Fas 6975351 Abnormal Lymph Node Morphology Faslpr>/Fas AK.MRL-Fas 6609979 Enlarged Lymph Nodes Faslpr>/Fas AK.MRL-Fas 6609979 Increased Immunoglobulin Level Faslpr>/Fas AK.MRL-Fas 6609979 Glomerulonephritis Faslpr>/Fas AK.MRL-Fas 6609979 Abnormal Renal Glomerulus Morphology Faslpr>/Fas AK.MRL-Fas 6609979 Increased Autoantibody Level Faslpr>/Fas AK.MRL-Fas 6609979 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas AK.MRL-Fas 6609979 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas AK.MRL-Fas 6609979 Abnormal Vagina Morphology Faslpr>/Fas C3.MRL-Fas 10453074 Abnormal T Cell Physiology Faslpr>/Fas C3.MRL-Fas 3009614 Salivary Gland Inflammation Faslpr>/Fas C3.MRL-Fas 1565490 Abnormal T Cell Proliferation Faslpr>/Fas C3.MRL-Fas 3009614 Decreased Apoptosis Faslpr>/Fas C3.MRL-Fas 10453074 Decreased Neuron Apoptosis Faslpr>/Fas C3.MRL-Fas 11567045 Abnormal T Cell Morphology Faslpr>/Fas C3.MRL-Fas 3009614 Abnormal Interleukin Level Faslpr>/Fas C3.MRL-Fas 3009614 Lacrimal Gland Inflammation Faslpr>/Fas C3.MRL-Fas 1565490 Premature Death Faslpr>/Fas MRL/MpJ-Fas 17574818,18492657 Autoimmune Response Faslpr>/Fas MRL/MpJ-Fas 17574818 Vascular Inflammation Faslpr>/Fas MRL/MpJ-Fas 18492657 Enlarged Lymph Nodes Faslpr>/Fas MRL/MpJ-Fas 18492657 Enlarged Spleen Faslpr>/Fas MRL/MpJ-Fas 18492657 Increased Immunoglobulin Level Faslpr>/Fas MRL/MpJ-Fas 17574818 Decreased Activated T Cell Number Faslpr>/Fas MRL/MpJ-Fas 18492657 Decreased B Cell Number Faslpr>/Fas MRL/MpJ-Fas 18492657 Glomerulonephritis Faslpr>/Fas MRL/MpJ-Fas 17574818,18055812,18492657 Increased Double-negative T Cell Number Faslpr>/Fas MRL/MpJ-Fas 18492657 Abnormal Leukocyte Adhesion Faslpr>/Fas MRL/MpJ-Fas 11971023 Abnormal Leukocyte Rolling Faslpr>/Fas MRL/MpJ-Fas 11971023 Increased Autoantibody Level Faslpr>/Fas MRL/MpJ-Fas 18492657 Increased Anti-nuclear Antigen Antibody Level Faslpr>/Fas MRL/MpJ-Fas 18492657 Decreased CD4-positive T Cell Number Faslpr>/Fas MRL/MpJ-Fas 18492657 Decreased CD8-positive T Cell Number Faslpr>/Fas MRL/MpJ-Fas 18492657 Abnormal Leukocyte Morphology Faslpr>/Fas MRL/MpJ-Fas 11971023 Premature Death Faslpr>/Fas MRL.Cg-Tnfrsf9 Fas 17608689 Skin Lesions Faslpr>/Fas MRL.Cg-Tnfrsf9 Fas 17608689 Increased Susceptibility To Bacterial Infection Faslpr>/Fas involves: MRL/Mp 9820556 Abnormal Macrophage Physiology Faslpr>/Fas involves: MRL/Mp 19741297 Increased Sensitivity To Induced Morbidity/mortality Faslpr>/Fas involves: MRL/Mp 9820556 Enlarged Spleen Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Increased IgA Level Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Increased IgM Level Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Increased Anti-double Stranded DNA Antibody Level Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Increased Anti-single Stranded DNA Antibody Level Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Lymph Node Hyperplasia Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Increased IgG1 Level Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Increased IgG2a Level Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Increased IgG2b Level Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079 Increased IgG3 Level Faslpr>/Fas involves: C57BL/6 * MRL/Mp 11737079