Primary Info
Mouse studies
DNA sequencing

mRNA IDs Primary Information
NM_002163.2 Gene Symbol IRF8
Protein Name interferon regulatory factor 8
Alternate Names H-ICSBP, ICSBP, ICSBP1, IRF-8
Gene Locus 16q24.1

External links
IDR HPRD OMIM Entrez Gene NetPath Reactome PDB HGNC Ensembl Swiss-Prot RefDIC
- 03336 601565 3394 NetPath_M3394 3394 -
5358 ENSG00000140968 Q02556 IRF8

Disease name Characteristic / Associated features Category inheritance type
IRF8 deficiency Susceptibility to Mycobacterial infections; oral candidiasis; cachexia; monocytopenia; disseminated BCG disease; severe immunodeficiency; impaired differentiation of mononuclear phagocytes; lack of dendritic cells Congenital defects of Phagocyte number, function or both Autosomal dominant