Resource of Asian Primary Immunodeficiency Diseases

RAPID Original

IFNGR2

External links	Primary Information
MGI:107654 ENSMUSG00000022965	Gene Symbol	Ifngr2
	Affected Anatomical Systems	hematopoietic system phenotype,homeostasis/metabolism phenotype,immune system phenotype
Allele Details
Allele ID Allele Symbol Allele Type Allele Name PubMed Id MGI:1930965 Ifngr2tm1Pbro Targeted (knock-out) targeted mutation 1, Paul B Rothman 9653170
Phenotypic Details
Phenotypes Allelic Composition Genetic Background PubMed Id Increased Susceptibility To Bacterial Infection Ifngr2tm1Pbro>/Ifngr2 involves: 129S1/Sv 9653170 Decreased Susceptibility To Type IV Hypersensitivity Reaction Ifngr2tm1Pbro>/Ifngr2 involves: 129S1/Sv 9653170 Abnormal Class Switch Recombination Ifngr2tm1Pbro>/Ifngr2 involves: 129S1/Sv 9653170 Abnormal T-helper 1 Cell Differentiation Ifngr2tm1Pbro>/Ifngr2 involves: 129S1/Sv 9653170 Abnormal T-helper 2 Physiology Ifngr2tm1Pbro>/Ifngr2 NOD.129S1-Ifngr2 11118001 Abnormal Cytotoxic T Cell Physiology Ifngr2tm1Pbro>/Ifngr2 NOD.129S1-Ifngr2 11714835 Decreased Susceptibility To Autoimmune Diabetes Ifngr2tm1Pbro>/Ifngr2 NOD.129S1-Ifngr2 11714835